3-[3-(Pyridin-3-yl)-1,2,4-oxadiazol-5-yl]propanoic acid
نویسندگان
چکیده
In the title compound, C(10)H(9)N(3)O(3), the benzene ring is almost coplanar with the heterocyclic ring, making a dihedral angle of 11.3 (1)°. The plane of the carboxyl group is rotated by 8.4 (2)° with respect to the 1,2,4-oxadiazole ring plane. The aliphatic chain exhibits an extended conformation. In the crystal, mol-ecules are liked through inter-molecular O-H⋯N bonds, forming a chain structure along the c axis.
منابع مشابه
Alum Catalyzed Simple, Efficient, and Green Synthesis of 2-[3-Amino-5-methyl-5-(pyridin-3-yl)-1,5-dihydro-4H-1,2,4-triazol-4-yl]propanoic Acid Derivatives in Aqueous Media
Alum (KAl(SO4)2 · 12H2O) is an inexpensive, efficient, and nontoxic catalyst used for the synthesis of 2-[3-amino-5-methyl-5-(pyridin-3-yl)-1,5-dihydro-4H-1,2,4-triazol-4-yl]propanoic acid derivatives in aqueous media by the reaction of 3-acetyl pyridine (1), amino acids (2)/(6), and thiosemicarbazide (4) at 80 °C. This methodology offers significant improvements for the synthesis of products w...
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عنوان ژورنال:
دوره 67 شماره
صفحات -
تاریخ انتشار 2010